Find the Best Supplement Brands
Trust scores, price ratings, and lab-testing grades for 26 supplement vendors — from NSF-certified industry leaders to brands you should avoid.
Top-Rated Supplement Brands
A / A+ Tier
Nootropics Depot
One of the most established and transparent supplement retailers in the industry. Nootropics Depot conducts rigorous in-house HPLC testing on all products and publishes COAs directly on their website, covering nootropics, vitamins, and herbal extracts.
Thorne Research
One of the most rigorously tested supplement brands available. Thorne holds NSF Certified for Sport status, manufactures in an NSF-registered facility, and is the official supplement partner of the Mayo Clinic and multiple elite sports organizations. Trusted by professional athletes subject to anti-doping testing.
Pure Encapsulations
Practitioner-grade supplement brand known for hypoallergenic, clean-label formulations with no unnecessary fillers, binders, or artificial ingredients. Widely recommended by integrative and functional medicine physicians. NSF Certified and manufactured in an NSF-GMP registered facility.
NOW Foods
One of the most established and value-oriented supplement manufacturers in the US, in business since 1968. NOW operates its own GMP-certified manufacturing facilities and conducts rigorous in-house testing on raw materials and finished products. Covers virtually every supplement category at competitive prices.
Garden of Life
Organic, whole-food-based supplement brand best known for its plant protein powders, probiotics, and whole-food vitamins. NSF Certified for Sport across its sport product line. Products are USDA Organic, Non-GMO Project Verified, and formulated without synthetic isolates.
Nordic Naturals
The leading brand in the omega-3 and fish oil segment. Nordic Naturals sources from sustainable wild-caught fish, uses triglyceride form for superior absorption, and third-party tests every batch for purity, potency, and oxidation. Consistently ranked #1 by independent omega-3 testing organizations.
Life Extension
Science-based supplement brand focused on longevity and preventive health, operating since 1980. Conducts rigorous third-party testing and publishes extensive research literature supporting formulations. One of the most comprehensive vitamin and mineral lines available with a strong scientific backing.
Designs for Health
Practitioner-exclusive supplement brand distributed primarily through licensed healthcare providers. Designs for Health focuses on therapeutic-grade formulations backed by clinical research. Known for superior bioavailability forms — methylated B vitamins, magnesium glycinate, and highly concentrated fish oil.
Solid Mid-Tier Brands
B / B+ TierJarrow Formulas
Well-established, science-forward supplement brand offering a broad range of clinically studied formulations at competitive prices. Jarrow is known for high-quality probiotics, creatine, and fish oil products. Consistently recommended by independent reviewers for balancing formula quality with accessible pricing.
Solgar
Heritage supplement brand founded in 1947 with a focus on natural, science-backed formulations. Solgar products are manufactured under strict GMP conditions and use high-quality raw materials. Well-known for fish oil, vitamin D, and magnesium products. Slightly premium priced but reliable for most supplement categories.
Klean Athlete
Sports-focused supplement brand where every single product carries NSF Certified for Sport certification. Designed specifically for athletes subject to anti-doping testing. Clean, straightforward formulas without unnecessary additives — creatine, protein, BCAAs, and pre-workout made with tested purity.
Optimum Nutrition
The world's best-selling whey protein brand and a long-standing staple in the sports nutrition industry. Gold Standard Whey is the benchmark protein powder globally. Owned by Glanbia, products are widely available and competitively priced. Quality is consistent and label accuracy is reliable.
Legion Athletics
Science-based sports supplement brand known for fully transparent labels, clinically effective doses, and zero proprietary blends. Founded by Mike Matthews (author of Bigger Leaner Stronger). Whey+ protein and Pulse pre-workout are among the most reviewed products in their segments for label accuracy.
Dymatize
Mid-tier sports nutrition brand owned by Post Holdings with a long history in protein powders and performance supplements. ISO100 Hydrolyzed Whey Protein is a well-reviewed product. Quality controls are above average for the price point. Products are widely available at major retailers.
MyProtein
UK-founded sports nutrition brand and one of Europe's largest supplement retailers, offering an extensive catalog at highly competitive prices. Impact Whey Protein is one of the best-selling protein powders globally. Quality is generally solid but has faced occasional minor consistency issues. Strong value for the price.
BulkSupplements
Raw ingredient supplement supplier offering no-frills, unflavored compounds in bulk quantities at the lowest prices in the market. Products are tested in-house and third-party verified for purity. Best suited for experienced users who want pure ingredients without paying for branding, flavoring, or packaging.
Swanson Vitamins
Affordable vitamin and supplement retailer offering a wide catalog of house-brand and third-party products since 1969. Swanson provides decent quality at below-market prices. Products carry GMP certification and in-house testing. Best suited for basic vitamin and mineral supplementation on a budget.
Nutricost
Budget-friendly supplement brand offering no-frills, single-ingredient products at competitive prices. Nutricost focuses on manufacturing basics — creatine, vitamins, amino acids — with GMP certification and third-party testing. Products are simple, well-dosed, and consistently below market pricing.
Brands to Avoid
C / D / F TierThese brands have significant quality, transparency, or regulatory concerns. See individual pages for details.
GNC
The largest specialty supplement retail chain in the US. GNC carries a wide range of brands but is known for its own house-brand products, which often use proprietary blends and are priced above market average. Quality controls are inconsistent across the catalog. Better used as a retail destination than as a trusted brand.
Onnit
Lifestyle supplement brand focused on cognitive performance and total human optimization. Best known for Alpha Brain, a nootropic supplement popularized by Joe Rogan's podcast. Products are heavily marketed and priced at a significant premium with limited evidence of superiority over less expensive alternatives.
Cellucor
Sports nutrition brand best known for the C4 pre-workout line — one of the best-selling pre-workout products globally. Owned by Nutrabolt. C4 is effective at the standard dose but uses some proprietary sub-blends. Protein and creatine products are average quality at above-market pricing.
MusclePharm
Sports nutrition brand that peaked in popularity during the early 2010s. MusclePharm has faced regulatory scrutiny including an FDA warning letter, quality control issues, and financial instability. Products use proprietary blends and quality has been inconsistent. Not recommended as a primary supplement vendor.
BPI Sports
Sports nutrition brand based in Florida known for BCAAs and pre-workout products. BPI relies heavily on proprietary blends, making it difficult to assess true ingredient dosages. Marketing is aggressive relative to the actual formulation quality. Products are mid-priced with below-average transparency.
MuscleTech
One of the most heavily marketed supplement brands in history, known for bold claims and large advertising budgets. MuscleTech products frequently use proprietary blends, oversized label claims, and inflated suggested retail pricing. The brand has faced numerous regulatory actions and advertising claim controversies over two decades.
Force Factor
Boston-based supplement brand known for aggressive TV infomercial and retail marketing. Force Factor products are heavily promoted with bold efficacy claims. Formulations heavily rely on proprietary blends, and independent testing has identified label accuracy issues. Sold primarily through GNC, Walmart, and Amazon at inflated price points.
Shredz
Influencer-driven fitness supplement brand that gained attention through aggressive Instagram marketing in the early 2010s. Shredz has faced FTC action for deceptive advertising and was ranked among the least reliable supplement brands by multiple independent reviewers. Products are significantly overpriced for the ingredient quality.
Compare by Product
93 results| Vendor | Product | Price | Mkt Avg | vs Market | Trust |
|---|---|---|---|---|---|
| BCAA 2:1:1 500g | $20.00 | $34.00 | -$14.00 | C TIER | |
| Impact Whey Protein 5.5lb | $52.00 | $65.00 | -$13.00 | C TIER | |
| Magnesium Glycinate 500g | $22.00 | $34.00 | -$12.00 | C TIER | |
| Pre-Workout MYPRE 2.0 30sv | $28.00 | $38.00 | -$10.00 | C TIER | |
| BCAA 2:1:1 Powder 400g | $18.00 | $28.00 | -$10.00 | C TIER | |
| Creatine Monohydrate 500g | $13.00 | $22.00 | -$9.00 | C TIER | |
| Creatine Monohydrate 500g | $14.00 | $22.00 | -$8.00 | C TIER | |
| BCAA 2:1:1 250g | $18.00 | $26.00 | -$8.00 | C TIER | |
| Creatine Monohydrate 500g | $14.00 | $22.00 | -$8.00 | C TIER | |
| Probiotic Multi-Action 30ct | $16.00 | $24.00 | -$8.00 | C TIER | |
| Magnesium 500mg 240ct | $14.00 | $22.00 | -$8.00 | C TIER | |
| Creatine Monohydrate 500g | $18.00 | $24.00 | -$6.00 | A TIER | |
| Vitamin D3 250ct | $8.00 | $14.00 | -$6.00 | C TIER | |
| Ultra Omega-3 Fish Oil 120ct | $14.00 | $20.00 | -$6.00 | C TIER | |
| Vitamin D3 5000 IU 365ct | $10.00 | $16.00 | -$6.00 | C TIER | |
| Elite 100% Whey Protein 5lb | $60.00 | $65.00 | -$5.00 | B TIER | |
| Vitamin D-3 5000 IU 250ct | $9.00 | $14.00 | -$5.00 | C TIER | |
| Magnesium Citrate 200mg 60ct | $7.00 | $12.00 | -$5.00 | C TIER | |
| Combat Whey Protein 5lb | $60.00 | $65.00 | -$5.00 | E TIER | |
| Whey Protein Concentrate 2lb | $28.00 | $32.00 | -$4.00 | A TIER | |
| Ultra Omega-3 90ct | $16.00 | $20.00 | -$4.00 | A TIER | |
| Vitamin D-3 5000 IU 120ct | $10.00 | $14.00 | -$4.00 | A TIER | |
| Creatine Monohydrate 500g | $22.00 | $26.00 | -$4.00 | B TIER | |
| EPA-DHA Balance 120ct | $22.00 | $26.00 | -$4.00 | B TIER | |
| Gold Standard Pre-Workout 30sv | $38.00 | $42.00 | -$4.00 | B TIER | |
| Gold Standard 100% Whey 5lb | $62.00 | $65.00 | -$3.00 | B TIER | |
| ISO100 Hydrolyzed Whey 5lb | $72.00 | $75.00 | -$3.00 | B TIER | |
| ISO HD Protein 4lb | $62.00 | $65.00 | -$3.00 | E TIER | |
| Dr. Formulated Probiotics 30ct | $32.00 | $34.00 | -$2.00 | A TIER | |
| Sport Multi+ 30ct | $34.00 | $36.00 | -$2.00 | A TIER | |
| Mega EPA/DHA 120ct | $28.00 | $30.00 | -$2.00 | A TIER | |
| Saccharomyces Boulardii Probiotic 90ct | $28.00 | $30.00 | -$2.00 | B TIER | |
| Vitamin D3 2500 IU 100ct | $10.00 | $12.00 | -$2.00 | B TIER | |
| Micronized Creatine 634g | $24.00 | $26.00 | -$2.00 | B TIER | |
| Essential BCAA 2:1:1 375g | $28.00 | $30.00 | -$2.00 | B TIER | |
| Creatine Monohydrate 300g | $16.00 | $18.00 | -$2.00 | B TIER | |
| Assault Pre-Workout 30sv | $40.00 | $42.00 | -$2.00 | E TIER | |
| 1MR Vortex Pre-Workout 25sv | $36.00 | $38.00 | -$2.00 | E TIER | |
| Nitro-Tech Whey Protein 4lb | $60.00 | $62.00 | -$2.00 | F TIER | |
| Platinum Creatine Monohydrate 400g | $22.00 | $24.00 | -$2.00 | F TIER | |
| Vitamin D3 with Sea-Iodine 60ct | $14.00 | $15.00 | -$1.00 | A TIER | |
| Creatine Monohydrate 90ct | $36.00 | $36.00 | -$0.00 | S TIER | |
| B-Complex #12 90ct | $32.00 | $32.00 | -$0.00 | S TIER | |
| Vitamin D3+K2 30ct | $18.00 | $18.00 | -$0.00 | A TIER | |
| Vitamin D3 5000 IU 120ct | $18.00 | $18.00 | -$0.00 | A TIER | |
| Magnesium L-Threonate 90ct | $38.00 | $38.00 | -$0.00 | A TIER | |
| Two-Per-Day Multivitamin 120ct | $30.00 | $30.00 | -$0.00 | A TIER | |
| Lactobacillus Acidophilus Probiotic 60ct | $22.00 | $22.00 | -$0.00 | B TIER | |
| Whey+ Isolate Protein 2lb | $50.00 | $50.00 | -$0.00 | B TIER | |
| BCAA Essentials 200ct | $28.00 | $28.00 | -$0.00 | E TIER | |
| Ultimate Omega 2X 60ct | $36.00 | $35.00 | +$1.00 | A TIER | |
| Sport Organic Plant Protein 2lb | $38.00 | $36.00 | +$2.00 | A TIER | |
| ProOmega 2000 60ct | $42.00 | $40.00 | +$2.00 | A TIER | |
| Vitamin D3 4000 IU 60ct | $16.00 | $14.00 | +$2.00 | B TIER | |
| Chelated Magnesium 100ct | $22.00 | $20.00 | +$2.00 | B TIER | |
| Recharge Creatine 60sv | $40.00 | $38.00 | +$2.00 | B TIER | |
| Pulse Pre-Workout 30sv | $52.00 | $50.00 | +$2.00 | B TIER | |
| Forge BCAA+HMB 30sv | $40.00 | $38.00 | +$2.00 | B TIER | |
| Best BCAA 30sv | $30.00 | $28.00 | +$2.00 | E TIER | |
| Vapor X5 Pre-Workout 30sv | $44.00 | $42.00 | +$2.00 | F TIER | |
| Magnesium Glycinate 90ct | $35.00 | $32.00 | +$3.00 | A TIER | |
| Vitamin D/K2 90ct | $26.00 | $22.00 | +$4.00 | S TIER | |
| Vitamin D3 5000 IU 90ct | $26.00 | $22.00 | +$4.00 | A TIER | |
| B-Complex Plus 90ct | $36.00 | $32.00 | +$4.00 | A TIER | |
| Omega-3 Phospholipids 60ct | $44.00 | $40.00 | +$4.00 | A TIER | |
| Magnesium Malate 120ct | $32.00 | $28.00 | +$4.00 | A TIER | |
| Omega-3 700 EPA & DHA 60ct | $32.00 | $28.00 | +$4.00 | B TIER | |
| Klean Creatine 60ct | $34.00 | $30.00 | +$4.00 | B TIER | |
| Klean BCAA + Peak ATP 30sv | $42.00 | $38.00 | +$4.00 | B TIER | |
| Klean Pre-Workout 30sv | $44.00 | $40.00 | +$4.00 | B TIER | |
| C4 Original Pre-Workout 30sv | $42.00 | $38.00 | +$4.00 | D TIER | |
| B-Supreme 60ct | $38.00 | $32.00 | +$6.00 | A TIER | |
| Klean Isolate Protein 1.6lb | $58.00 | $52.00 | +$6.00 | B TIER | |
| COR-Performance Whey 4lb | $58.00 | $52.00 | +$6.00 | D TIER | |
| CRE-A Sport Creatine 30sv | $28.00 | $22.00 | +$6.00 | D TIER | |
| EPA/DHA Essentials 90ct | $45.00 | $38.00 | +$7.00 | A TIER | |
| Super EPA Fish Oil 90ct | $46.00 | $38.00 | +$8.00 | S TIER | |
| OmegAvail Ultra TG 120ct | $52.00 | $44.00 | +$8.00 | A TIER | |
| C4 Ultimate Pre-Workout 20sv | $50.00 | $42.00 | +$8.00 | D TIER | |
| Total Lean Pre-Workout 30sv | $52.00 | $42.00 | +$10.00 | D TIER | |
| GNC Mega Men Multivitamin 90ct | $38.00 | $28.00 | +$10.00 | D TIER | |
| Volcano Pre-Workout 30sv | $52.00 | $42.00 | +$10.00 | F TIER | |
| New Mood 30ct | $30.00 | $18.00 | +$12.00 | D TIER | |
| Shredz Pre-Workout 30sv | $50.00 | $38.00 | +$12.00 | F TIER | |
| Pro Performance Whey 5lb | $78.00 | $65.00 | +$13.00 | D TIER | |
| GNC AMP Creatine 90ct | $42.00 | $28.00 | +$14.00 | D TIER | |
| SCORE! Testosterone Booster 60ct | $50.00 | $30.00 | +$20.00 | F TIER | |
| Onnit Whey Protein 2lb | $60.00 | $38.00 | +$22.00 | D TIER | |
| Test X180 Alpha Max 120ct | $60.00 | $35.00 | +$25.00 | F TIER | |
| Shredz Protein Powder 2lb | $60.00 | $35.00 | +$25.00 | F TIER | |
| Total Human Day Pack 30ct | $82.00 | $50.00 | +$32.00 | D TIER | |
| Alpha Brain 90ct | $80.00 | $45.00 | +$35.00 | D TIER | |
| Burner for Her 60ct | $55.00 | $20.00 | +$35.00 | F TIER |